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In addition, the indole Main is substituted at R3 which has a carbonyl team which is also bonded to the napthalene moeity. Napthalene is often a bicyclic construction of two fused benzene rings. This carbonyl bridge of JWH-018 classifies it as a ketone. JWH-018 is an analog of THJ-018, wherein the core indazole composition is substituted using an i